If spots or lines appear in all your scanned images, try these
solutions:
Make sure the surface of the original clean.
Make sure there is no debris or dirt inside the ADF.
Disconnect any connected cables and clean inside the
scanner.
Enable the Detect Glass Dirt
setting on the control panel. (Press the home button, select
Settings > Scanner Settings > Detect Glass Dirt, and select On-Low, if the alert displays a misdetection, or
On- High if dirt is not detected.)
When an alert displays on the control panel, clean the glass
scanning surfaces inside your scanner using a genuine Epson
cleaning kit or a soft, moist cloth.
Note: If there are
scratches on the glass surface, the alert screen may continue to
appear even after cleaning the glass. Contact Epson for information
about replacing the glass.