If you cannot start EPSON Scan, try these solutions:
Windows: Click or
Start > All Programs or Programs > EPSON > EPSON
Scan > EPSON Scan
Settings. Make sure the correct Connection setting is selected, then click the
Test button.
Mac OS X: Open the Applications folder, click Epson Software, and click EPSON Scan Settings. Make sure the correct Connection setting is selected, then click the Test button.